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Associate Principal Scientist, Computational Chemistry Job Opening In Lima Metropolitana – Now Hiring Neomorph, Inc.


Job description

Overview

Associate Principal Scientist, Computational Chemistry – Neomorph

Neomorph is seeking an experienced Associate Principal Scientist to join our Computational Chemistry team.

This individual contributor role thrives in a fast-paced startup environment and focuses on targeted protein degradation and small molecule drug discovery.

You will advance discovery programs from target assessment through candidate nomination and partner with medicinal chemistry, structural biology, biophysics, and biology to integrate computational strategies into program decision-making.

You will also help evolve Neomorph’s computational capabilities by championing innovation and deploying novel tools and methods.

Key Responsibilities

  • Serve as a scientific lead and primary computational chemistry contributor on one or more drug discovery programs, guiding design strategies through all phases of the discovery process.

  • Integrate structure- and ligand-based design, cheminformatics, and predictive modeling to accelerate hit identification, hit-to-lead, and lead optimization.

  • Design and prioritize novel compounds using hypothesis-driven approaches informed by structural data, SAR, molecular modeling, and ML/AI tools.

  • Apply and enhance computational chemistry methodologies, including protein–ligand docking, molecular dynamics (MD), free energy calculations, and ADMET prediction.

  • Collaborate cross-functionally to influence program strategy and compound design, bringing depth and creativity to design hypotheses.

  • Explore and evaluate new computational tools, workflows, and platforms to expand Neomorph’s internal capabilities.

  • Mentor and provide scientific guidance to colleagues across functions; contribute to project team leadership through influence.

  • Present findings and strategic recommendations to cross-functional teams and scientific leadership.

Required Qualifications

  • PhD in Computational Chemistry, Theoretical Chemistry, or a related field with 6+ years, MS with 9+ years, or BS with 12+ years of relevant industry experience in drug discovery.

  • Demonstrated impact as a lead computational chemist on drug discovery programs, including contributions to compound progression and decision-making.

  • Deep expertise in structure-based drug design, molecular modeling, and ligand-based approaches; working knowledge of medicinal chemistry principles.

  • Hands-on experience with molecular dynamics simulations (AMBER, GROMACS, OpenMM) and free energy calculations (FEP+, TI, MM-GBSA).

  • Proficiency in relevant software suites (e.g., Schrödinger, OpenEye) and scripting/programming languages (Python, R).

  • Proven ability to integrate complex data and translate computational insights into actionable recommendations.

  • Strong communication, collaboration, and problem-solving skills with the ability to influence cross-functional teams and drive strategic discussions.

Preferred Qualifications

  • Experience applying generative AI, machine learning, or advanced cheminformatics techniques to small molecule design.

  • Familiarity with targeted protein degradation or protein–protein interaction drug discovery.

  • Experience developing and optimizing cloud-based computational workflows.

  • Knowledge of quantum chemistry methods, bioinformatics tools, and/or data integration strategies.

What we offer

  • Industry-competitive compensation
  • Annual target bonus
  • Stock option
  • 401K plan
  • Career advancement opportunities
  • Monthly town halls to share business and scientific updates

Work/Life and Benefits

  • Comprehensive medical, dental, and vision plans for employees and dependents
  • Health Savings Account (HSA) and Flexible Spending Account (FSA) options
  • Employee Assistance Program
  • Paid holidays, winter shutdown, vacation time, sick leave, and parental leave options
  • Casual work environment and volunteer days off
  • Onsite gym and facilities

About Us

Neomorph is a venture-backed biotechnology company solving critical problems in human health through discovery and development of medicines against undruggable targets.

We are leaders in protein degradation and molecular glue drug discovery, committed to advancing science and technology while pursuing a diverse, inclusive work environment.

Neomorph is headquartered in San Diego, California, and is an equal opportunity employer.

We comply with all applicable laws and do not discriminate on protected characteristics.

Note to agencies: Neomorph will not accept unsolicited assistance from recruiting/search agencies for this opportunity.

All resumes submitted without a valid written agreement will be deemed the property of Neomorph.

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Required Skill Profession

Otros


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Unlock Your Associate Principal Potential: Insight & Career Growth Guide


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Are You Looking for Associate Principal Scientist, Computational Chemistry Job?

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The Work Culture

An organization's rules and standards set how people should be treated in the office and how different situations should be handled. The work culture at Neomorph, Inc. adheres to the cultural norms as outlined by Expertini.

The fundamental ethical values are:

1. Independence

2. Loyalty

3. Impartiapty

4. Integrity

5. Accountabipty

6. Respect for human rights

7. Obeying Peru laws and regulations

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Other Openings

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